Fel-o-Vax PCT is prepared from feline rhinotracheitis, calici, and panleukopenia which have been grown on feline kidney tissue cell line and inactivated with formaldehyde.  The antigens have been combined and an adjuvant added for convenient administration to cats of all ages. Prior to inactivation of the viruses, the tissue culture fluids are filtered to remore cellular debris, often responsible for tissue reactions, and to assist in complete inactivation of the viruses.

This product has been tested and shown to be satisfactory for marketing in accordance with procedures required by the U.S. Department of Agriculture.

Feline rhinotracheitis and calici viruses both cause an upper respiratory tract infection in susceptible cats of all ages. The rhinotracheitis virus affects the epithelial surface of the upper respiratory passages and conjunctiva, which frequently causes hypersalivation, coughing and sneezing. Ocular discharge is a common symptom associated with the infection.

Calici virus infections are recognized by ulcerative lesions in the oral cavity, tongue epithelium and the nose. Both rhinotracheitis and calici viruses cause serious, and occasionally fatal, disease in susceptible cats, but are most pronounced in young kittens.

Feline panleukopenia infection usually results in an acute fulminating disease with high mortality, especially in kittens; however, subclinical or mild cases can be common under certain conditions. Symptoms include depression, anorexia, vomiting, weight loss and diarrhea, which is frequently accompanied by blood-tinged feces. In young kittens the virus causes cerebellar hypoplasia characterized by incoordination, staggering, and rolling. Such kittens have been exposed in utero or shortly after birth.